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Establishment of a Four Layer Complicated Ellipsoid Brain Model |
1 School of Electrical Engineering, Shenyang University of Technology, Shenyang 110870, China
2 School of SinoDutch Biomedical & Information Engineering, Northeastern University, Shenyang 110819, China
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Abstract The study of brain model establishment is the basis of intracranial imaging, and it is also the necessary condition for the calculation of forward problem solution in the magnetic induction tomography (MIT) system. According to the brain structure, a four layers complicated ellipsoid brain model was established through a finite element simulation software Comsol Multiphysics. Firstly, the brain parenchyma model was constructed according to the brain volume and the skull inner diameter. Secondly, the skull model was constructed according to the human anatomy structureand the contour, occipital, frontal and orbit of the model were corrected. Thirdly, the head cortex, skull and spinal fluid layer were constituted by scale model of the skull, and the four layers brain model were constituted together with the brain parenchyma layer. Finally, put the model into alternating current magnetic field of 10 MHz, and gave the induced current distribution of scalp layer, skull layer, spinal fluid layer and parenchymal layer. The induced current was strongest in the spinal fluid layer and weaker in the skin layer and the parenchymal layer, while was the weakest in the skull layer. The ratio of the induced current density values in each layer was 32:1:190:21, closed to the ratio of electrical conductivity. The simulation experimental results showed that the model could display the difference of the electromagnetic characteristics of human head tissues, providing reliable data for MIT system.
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[1]Yasin M. Imaging of hemorrhagic stroke in magnetic induction tomography: an in vitro study [J]. International Journal of Imaging Systems and Technology, 2014, 24(2): 161-166.
[2]Wilson FN, Bayley RH. The electric field of an eccentric dipole in a homogeneous spherical conducting medium [J]. Circulation, 1950, 1(1): 84-92.
[3]Cuffin BN, Cohen D. Comparison of the magnetoencephalogram and electroencephalogram [J]. Electroencephalography and Clinical Neurophysiology, 1979, 47(2): 132-146.
[4]柯丽,赵璐璐,杜强. 颅脑血肿MIT涡流场仿真与分析[J].系统仿真学报,2014,26(3):517-522.
[5]Huang MX, Mosher JC, Leahy RM. A sensorweighted overlappingsphere head model and exhaustive head model comparison for MEG [J]. Physics in Medicine and Biology, 1999, 44(2): 423-440.
[6]孙丰荣, 刘泽, 李艳玲, 等. 基于模型的CT三维医学图像重建仿真 [J]. 系统仿真学报, 2006, 18(3): 781-784.
[7]李烨, 董秀珍, 刘锐岗, 等. 磁感应断层成像中的一种高精度同步相位测量方法 [J]. 仪器仪表学报, 2009, 30(4): 796-801.
[8]秦明新. 检测脑水肿的磁感应成像测量方法研究 [D]. 西安: 西安电子科技大学, 2005.
[9]王雷. 脑磁感应断层成像正问题的三维有限元仿真研究 [D]. 西安: 第四军医大学, 2013.
[10]Dannhauer M, Lanfer B, Wolters CH, et al. Modeling of the human skull in EEG source analysis [J]. Human Brain Mapping, 2010, 32(9): 1383-1399.
[11]Bashar MR, Li Y, Wen P. Effects of local tissue conductivity on spherical and realistic head models [J]. Australasian Physical & Engineering Sciences in Medicine, 2010, 33(3): 233-242.
[12]Henery CC, Mayhew TM. The cerebrum and cerebellum of the fixed human brain: efficient and unbiased estimates of volumes and cortical surface areas [J]. Journal of Anatomy, 1989, 167: 167-180.
[13]柯丽,李盼盼,陈红.颅骨对磁感应断层成像信号检测影响的仿真与实验研究[J].中国生物医学工程学报,2015,34(5):566-573.
[14]柯丽,曹冯秋,杜强.MIT中反投影矩阵的计算与数据处理方法[J].仪器仪表学报,2014,35(10):2256-2262.
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