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| Modeling and Simulation of a Fifth-Order Lumped Parameter Cardiovascular System |
1 Institute of Biomedical Engineering, Jiangsu University Jiangsu 212013, China
2 IoT Engineering, Jiangnan University ,Jiangsu ,214000, China |
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Abstract In order to deeply understand the mechanisim of heart failure and provide therapy and simulation tool for clinical diagnosis and treatment, a fifth-order lumped parameter cardiovascular system model according to electrical circuit theory was built in this paper. Using MATLAB, the simulation results show that the model is effective and it can simulate the hemodynamics of normal heart. The simulated CO (Cardiac Output) is 5.12 L/min. Under different level exercises including mild exercise, moderate exercise and severe exercise, of normal heart the simulated CO gradually increase from 5.09 L/min, 8.86 L/min, 10.74 L/min to 14.7 L/min. The four categories of ClassⅠ, ClassⅡ, ClassⅢ, Class Ⅳ of heart failure can be also simulated by the method. The simulated CO decrease from 5 L/min, 4.4 L/min, 3.8 L/min to 3.2 L/min. The results of our studies agreed well with real physiological conditions and the experimental data reported in literatures. This is important for the diagnosis and treatment of heart diseases.
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