基于格兰杰因果性的行走状态下脑肌电同步分析

doi:10.3969/j.issn.0258-8021.2014. 06.09

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Abstract The aim of this study is to investigate functional relationship between brain cortex and muscles during walking and explore the differences of the functional relationships between forward and backward walking. This article collects the EEG and EMG datasets which acquired simultaneously from 10 healthy subjects during forward and backward walking. Granger causality (GC) method, which can reveal the coupling connection and information flow direction among two signals, was applied to analyze the EEG and surface EMG data. Further, the EEGEMG significant GC area was defined to quantitatively describe the corticomuscular function coupling and information flow direction of different muscles at different frequencies. Then the EEG spectral power was calculated to analyze the relationship with corticomuscular function coupling. The results of Wilcoxon test show that during backward walking, the EEG→EMG and EMG→EEG significant GC area indexes of rectus femoris and tibialis anterior muscle were lower compared with forward walking(α=005, P<005), and a linear relationship exists between EEG spectral power peak and GC peak at EEG→EMG based on linear regression analysis(α=005, P<005). These illustrate that there exists directed coupling between EEG and EMG during walking, and alpha and beta rhythm involve the control and feedback process of walking. It verifies that the proposed methods can further describe the synchronization feature and functional connection between cortex and muscles.

Key words： corticomuscular Granger causality (GC) significant GC area function coupling walking

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	NIU Xiao Chen¹ CHEN Xiao Ling¹CHEN Ying Ya¹WU Xiao Guang¹ DU Yi Hao²XIE Ping^1*

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NIU Xiao Chen¹ CHEN Xiao Ling¹CHEN Ying Ya¹WU Xiao Guang¹ DU Yi Hao²XIE Ping^1*. Corticomuscular Synchronization Analysis Based on Granger Causality during Walking#br#[J]. journal1, 2014, 33(6): 696-706.

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http://cjbme.csbme.org/EN/10.3969/j.issn.0258-8021.2014. 06.09 OR http://cjbme.csbme.org/EN/Y2014/V33/I6/696

［1］Gazzaniga MS, Ivry RB, Mangun GR，著. 周晓林，高定国，等译. 认知神经科学：关于心智的生物学［M］. 北京：中国轻工业出版社，2013：223-269.
［2］Wieser M, Haefeli J, Bütler L, et al. Temporal and spatial patterns of cortical activation during assisted lower limb movement ［J］. Exp Brain Res, 2010, 203(1): 181-191.［3］La Fougere C, Zwergal A, Rominger A, et al. Real versus imagined locomotion: A ［18F］-FDG PETfMRI comparison ［J］. Neuroimage, 2010, 504): 1589-1598. 
［4］Clark DJ, Kautz SA, Bauer AR, et al. Synchronous EMG activity in the piper frequency band reveals the corticospinal demand of walking tasks ［J］. Ann Biomed Eng, 2013, 41(8): 1778-1786.
［5］Petersen TH, WillerslevOlsen M, Conway BA, et al. The motor cortex drives the muscles during walking in human subjects ［J］. J Physiol, 2012, 590(10): 2443-2452.
［6］欧阳军. 回归自然的反常态运动［J］. 医疗保健器具, 2006 (2): 51-52. 
［7］Masumoto K, Takasugi S, Hotta N, et al. A comparison of muscle activity and heart rate response during backward and forward walking on an underwater treadmill ［J］. Gait & Posture, 2007, 25(2): 222-228.
［8］Masumoto K, Takasugi S, Hotta N, et al. Electromyographic analysis of walking in water in healthy humans ［J］. J Physiol Anthropol, 2004, 23(4): 119-127.
［9］Masumoto K, Takasugi S, Hotta N, et al. Muscle activity and heart rate response during backward walking in water and on dry land ［J］. Eur J Appl Physiol, 2005, 94(1-2): 54-61.
［10］郝卫亚, 陈严. 倒走的运动生物力学与生理学研究进展［J］. 中国运动医学杂志, 2008, 27(3): 390-392.
［11］Gwin JT, Gramann K, Makeig S, et al. Electrocortical activity is coupled to gait cycle phase during treadmill walking ［J］. Neuroimage, 2011, 54(2): 1289-1296.
［12］Claire LW, Riddle CN, Baker MR, et al. Contributions of descending and ascending pathways to corticomuscular coherence in humans ［J］. The Physiol Soc, 2011, 589(15): 3789-3800.
［13］Kristeva R, Patino L, Omlor W. Betarange cortical motor spectral power and corticomuscular coherence as a mechanism for effective corticospinal interaction during steadystate motor output ［J］. Neuroimage, 2007, 36(3): 785-792.
［14］Raethjen J, Govindan RB, Binder S, et al. Cortical representation of rhythmic foot movements ［J］. Brain Res, 2008, 1236: 79-84.
［15］Ushiyama J, Takahashi Y, Ushiba J. Muscle dependency of corticomuscular coherence in upper and lower limb muscles and trainingrelated alterations in ballet dancers and weightlifters ［J］. J Appl Physiol, 2010, 109(4): 1086-1095.
［16］Schelter B, Timmer J, Eichler M. Assessing the strength of directed influences among neural signals using renormalized partial directed coherence ［J］. J Neurosci Methods, 2009, 179(1): 121-130.
［17］Seth AK. A Matlab toolbox for Granger causal connectivity analysis ［J］. J Neurosci Methods, 2010, 186(2): 262-273.
［18］Sitnikova E, Dikanev T, Smirnov D, et al. Granger causality: corticothalamic interdependencies during absence seizures in WAG/Rij rats ［J］. J Neurosci Methods, 2008, 170(2): 245-254.
［19］Ding M, Chen Y, Bressler S L. Granger causality: basic theory and application to neuroscience ［M］. Handbook of Time Series Analysis. Zurich: Wiley\|VCH Velage, 2006: 451-474.
［20］Omlor W, Patino L, HeppReymond M C, et al. Gammarange corticomuscular coherence during dynamic force output ［J］. Neuroimage, 2007, 34(3): 1191-1198.
［21］Fang Y, Daly JJ, Sun J, et al. Functional corticomuscular connection during reaching is weakened following stroke ［J］. Clin Neurophysiol, 2009, 120(5): 994-1002.
［21］Welch PD. The use of fast Fourier transform for the estimation of power spectra: a method based on time averaging over short, modified periodograms ［J］. IEEE Trans Audio Electroacoust, 1967, 15（2): 70-73.
［22］Vecchio F, Del Percio C, Marzano N, et al. Functional corticomuscular coupling during upright standing in athletes and nonathletes: a coherence electroencephalographicelectromyographic study ［J］. Behav Neurosci, 2008, 122(4): 917.
［23］Pfurtscheller G, Lopes Da Silva FH. Eventrelated EEG/MEG synchronization and desynchronization: basic principles ［J］. Clin Neurophysiol, 1999, 110(1): 1842-1857. 
［24］Hansen NL, Nielsen JB. The effect of transcranial magnetic stimulation and peripheral nerve stimulation on corticomuscular coherence in humans ［J］. Journal Physiol, 2004, 561(1): 295-306.
［25］谢平, 陈晓玲, 苏玉萍, 等. 基于 EMD-多尺度熵和 ELM 的运动想象脑电特征提取和模式识别［J］. 中国生物医学工程学报, 2013, 32(6): 641-648.