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The Opportunities and Challenges of Deep Brain Stimulation in the Future |
1 Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 215163, Jiangsu,China
2 Brain Hospital in Tangdu Hospital, the Fourth Military Medical Universit, Xi’an 710038, China
3 Brain Hospital in Beijing Military General Hospital, Beijing 100700, China |
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Abstract The treatment of neurological and psychiatric diseases remains challenging with huge population and lack of effective medication. Deep brain stimulation is an alternative reliable clinical approach for many patients with Parkinson’s disease, pain, etc. There is urgent demand in improving the clinical performance of deep brain stimulation and expanding benefit for larger population. This paper presents perspectives in scientific questions, technologies and key advancements related to the deep brain stimulation, i.e., the mechanisms of neuromodulation, intelligent stimulation strategy, precise operation technique, new indications, quantitative and remote rehabilitation, devices with advanced technology and integrated management system. The goals of future development are to refine deep brain stimulation for existing indications, develop novel clinical approach for new indications, reduce the clinical cost, improve the quality of clinical service, and optimize the medical treatment.
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