上肢辅助站立状态下姿态扰动诱发的脑电响应特征

doi:10.3969/j.issn.0258-8021.2019.06.004

Abstract
Figure/Table
References
Related Citation (15)

Download: PDF (4178 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS)

Abstract This study investigated the characteristics of EEG response evoked by postural perturbation during standing with upper limb support, aiming to provide a new idea for detecting the instability of patients with lower extremity motor dysfunction. The experimental equipment was designed to apply rapid and sudden change of upper limb supporting force on random side of human body to simulate the perturbation during upper limb assisted standing. The EEG of 64 channels, two sides of supporting force andsurface electromyogram (sEMG) of smaller forearm extensors on both sides of 20 subjects were recorded synchronously. We analyzed the neural response characteristics of EEG evoked potential, and the behavioral response characteristics of mechanical signal and sEMG. Results: After the postural perturbation was applied, the supporting force on the perturbed side suddenly decreased in the time of (200.5±15.4) ms. Meanwhile, sEMG of smaller forearm extensors on both sides increased, and the sEMG of perturbed side was higher than the other side. Following postural perturbation onset, N1 potentials were observed with a peak latency of (62.3±5.5) ms and the peak activity was located at FCz electrode with a peak amplitude of (15.6±6.1) μV. The peak latency of P2 potentials were (167.4±12.4) ms and peak amplitude were (5.2±4.5) μV. The findings of this study provided a feasibility of detecting human unsteady state through neural response process.

Key words： lower extremity motor dysfunction postural perturbation EEG evoked potential N1

Received: 24 November 2018

PACS:

R318

Corresponding Authors: E-mail: richardming@tju.edu.cn

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	He Feng
	Zhang Jie
	Jiang Shenglong
	Qi Hongzhi
	Xu Rui
	Meng Lin
	Ming Dong

Cite this article:

He Feng,Zhang Jie,Jiang Shenglong, et al. Characteristics of EEG Response Evoked by Postural Perturbation During Standing with Upper Limb Support[J]. Chinese Journal of Biomedical Engineering, 2019, 38(6): 672-678.

URL:

http://cjbme.csbme.org/EN/10.3969/j.issn.0258-8021.2019.06.004 OR http://cjbme.csbme.org/EN/Y2019/V38/I6/672

[1] 张建, 华琦. 中国老龄化的特征发展趋势与对策[J]. 中国心血管杂志, 2010, 15(1): 79-80.
[2] Mihara M, Miyai I, Hatakenaka M, et al. Role of the prefrontal cortex in human balance control[J]. Neuroimage, 2008, 43(2): 329-336.
[3] Jacobs JV, Fujiwara K, Tomita H, et al. Changes in the activity of the cerebral cortex relate to postural response modification when warned of a perturbation[J]. Clinical Neurophysiology, 2008, 119(6): 1431-1442.
[4] Mochizuki G, Sibley KM, Esposito JG, et al. Cortical responses associated with the preparation and reaction to full-body perturbations to upright stability[J]. Clinical Neurophysiology, 2008, 119(7): 1626-1637.
[5] Mochizuki G, Sibley KM, Cheung HJ, et al. Generalizability of perturbation-evoked cortical potentials: Independence from sensory, motor and overall postural state[J]. Neuroscience Letters, 2009, 451(1): 40-44.
[6] Andreas M, Thorben H, Strüder HK. Changes in cortical activity associated with adaptive behavior during repeated balance perturbation of unpredictable timing[J]. Frontiers in Behavioral Neuroscience, 2015, 9: 1-12.
[7] Maki BE, Mcilroy WE. Cognitive demands and cortical control of human balance-recovery reactions[J]. Journal of Neural Transmission, 2007, 114(10): 1279-1296.
[8] Jacobs JV, Horak FB. Cortical control of postural responses[J]. Journal of Neural Transmission, 2007, 114(10): 1339-1348.
[9] Adkin AL, Campbell AD, Chua R, et al. The influence of postural threat on the cortical response to unpredictable and predictable postural perturbations[J]. Neuroscience Letters, 2008, 435(2): 120-125.
[10] 胡晓, 王志中, 任小梅. 小波变换和非线性分析在表面肌电信号中的应用及进展[J]. 北京生物医学工程, 2006, 25(1): 105-108.
[11] 基于表面肌电信号的手指活动模式检测[D]. 重庆:重庆大学, 2008.
[12] Ebrahimi T. Recent advances in brain-computer interfaces[C]//IEEE Workshop on Multimedia Signal Processing. Chania: IEEE, 2007: 17-24.
[13] Slobounov SM, Ray WJ. Movement-related potentials with reference to isometric force output in discrete and repetitive tasks[J]. Experimental Brain Research, 1998, 123(4):461-473.
[14] Dietz V, Quintern J, Berger W. Afferent control of human stance and gait: evidence for blocking of group I afferents during gait[J]. Experimental Brain Research, 1985, 61(1): 153-163.
[15] Dietz V, Quintern J, Berger W, et al. Cerebral potentials and leg muscle e.m.g. responses associated with stance perturbation[J]. Experimental Brain Research, 1985, 57(2): 348-354.
[16] Adkin AL, Quant S, Maki BE, et al. Cortical responses associated with predictable and unpredictable compensatory balance reactions[J]. Experimental Brain Research, 2006, 172(1): 85-93.
[17] Dietz V, Quintern J, Berger W. Cerebral evoked potentials associated with the compensatory reactions following stance and gait perturbation[J]. Neuroscience Letters, 1984, 50(1-3): 181-186.
[18] Varghese JP, Marlin A, Beyer KB, et al. Frequency characteristics of cortical activity associated with perturbations to upright stability[J]. Neuroscience Letters, 2014, 578: 33-38.
[19] Quant S, Adkin AL, Staines WR, et al. Cortical activation following a balance disturbance[J]. Experimental Brain Research, 2004, 155(3): 393-400.
[20] Van Veen V, Carter CS. The anterior cingulate as a conflict monitor: fMRI and ERP studies[J]. Physiology & Behavior, 2002, 77(4): 477-482.
[21] Holroyd CB, Mgh C. The neural basis of human error processing: Reinforcement learning, dopamine, and the error-related negativity[J]. Psychological Review, 2002, 109(4): 679-709.
[22] Gehring WJ, Goss B, Coles M, et al. The error-related negativity[J]. Perspectives on Psychological Science, 2011, 13(2): 200-204.
[23] Olvet DM, Hajcak G.The error-related negativity (ERN) and psychopathology: Toward an endophenotype[J]. Clinical Psychology Review, 2008, 28(8): 1343-1354.
[24] Falkenstein M, Hielscher H, Dziobek I, et al. Action monitoring, error detection, and the basal ganglia: an ERP study[J]. Neuroreport, 2001, 12(1): 157-161.
[25] Hajcak G, Mcdonald N, Simons RF. Anxiety and error-related brain activity[J]. Biological Psychology, 2003, 64(2): 77-90.
[26] Slobounov S, Cao C, Jaiswal N, et al.Neural basis of postural instability identified by VTC and EEG[J], Experimental Brain Research, 2009, 199(1): 1-16.
[27] Wessel JR.Error awareness and the error-related negativity: Evaluating the first decade of evidence[J]. Frontiers in Human Neuroscience, 2012, 6(6): 1-16.
[28] Dehaene S, Posner MI, Tucker DM. Localization of a neural system for error detection and compensation[J]. Psychological Science, 1994, 5(5): 303-305.
[29] Gehring WJ, Goss B, Coles MG, et al.A neural system for error detection and compensation[J]. Psychological Science, 1993, 4(6): 385-390.